Type of Document	Dissertation
Author	Al-Mudhaffar, Semi Abdul-Mohdi
URN	etd-01132010-020024
Title	Studies on the mechanism of action of thyroid hormones
Degree	PhD
Department	Biochemistry
Advisory Committee	Advisor Name Title Ackermann, Clemens J. Committee Chair King, Kendall W. Committee Member Webb, Ryland E. Committee Member
Keywords	enzymes thyroid hormones
Date of Defense	1967-08-06
Availability	unrestricted
Abstract Inosine monophosphate (IMP) is a precursor of the two purine nucleotides, adenosine monophosphate (AMP) and guanosine monophosphate (GMP)e through DEAE-Scphacex, and the reaction IMP~ XMP is catalyzed by: IMP dehydrogenase which was purified in a manner similar to adenylosuccinate synthetase. Adenylosuccinate synthetase of rat liver is stimulated maximally with 10-9 M L-T 3 or 10-5 M L-T4 , but not by D in vivo effects. Further correlation to in vivo studies was obtained from brain and testes tissues.
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