Title page for ETD etd-01132010-020024


Type of Document Dissertation
Author Al-Mudhaffar, Semi Abdul-Mohdi
URN etd-01132010-020024
Title Studies on the mechanism of action of thyroid hormones
Degree PhD
Department Biochemistry
Advisory Committee
Advisor Name Title
Ackermann, Clemens J. Committee Chair
King, Kendall W. Committee Member
Webb, Ryland E. Committee Member
Keywords
  • enzymes
  • thyroid hormones
Date of Defense 1967-08-06
Availability unrestricted
Abstract

Inosine monophosphate (IMP) is a precursor of the two purine nucleotides, adenosine monophosphate (AMP) and guanosine monophosphate (GMP)e through DEAE-Scphacex, and the reaction IMP~ XMP is catalyzed by: IMP dehydrogenase which was purified in a manner similar to adenylosuccinate synthetase. Adenylosuccinate synthetase of rat liver is stimulated maximally with 10-9 M L-T 3 or 10-5 M L-T4 , but not by D in vivo effects. Further correlation to in vivo studies was obtained from brain and testes tissues.

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