| Type of Document |
Master's Thesis |
| Author |
Flynn, Allison
|
| URN |
etd-03022010-020016 |
| Title |
Transition metals as anti-tumoral agents :some structure-function relationships of the platinum group metals |
| Degree |
Master of Science |
| Department |
Chemistry |
| Advisory Committee |
| Advisor Name |
Title |
| Merola, Joseph S. |
Committee Chair |
| Brewer, Karen J. |
Committee Member |
| Niehaus, Walter G. Jr. |
Committee Member |
|
| Keywords |
|
| Date of Defense |
1994-06-05 |
| Availability |
restricted |
Abstract
Since the discovery that cis-diamminedichloroplatinum (II) possessed great antitumor properties, researchers have been synthesizing and screening metal coordination complexes for their potential anti-tumor activity. Hundreds of compounds have been tested, and few compounds possessed anti-tumor activity. This paper examines how the physical and chemical properties of complexes of the platinum group metals affect their toxicity and anti-tumor activity.
|
| Files |
| Filename |
Size |
Approximate Download Time
(Hours:Minutes:Seconds)
|
| 28.8 Modem |
56K Modem |
ISDN (64 Kb) |
ISDN (128 Kb) |
Higher-speed Access |
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LD5655.V851_1994.F596.pdf |
1.99 Mb |
00:09:13 |
00:04:44 |
00:04:08 |
00:02:04 |
00:00:10 |
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