Title page for ETD etd-08012012-040709


Type of Document Dissertation
Author Walker, Clay B.
URN etd-08012012-040709
Title Experimental anaerobic bacterial infections in mice
Degree PhD
Department Microbiology
Advisory Committee
Advisor Name Title
Wilkins, Tracy D. Committee Chair
Cummins, C. S. Committee Member
Gregory, Eugene M. Committee Member
Krieg, Noel R. Committee Member
Moore, W. E. C. Committee Member
Keywords
  • infections
Date of Defense 1977-06-15
Availability restricted
Abstract
The development of a technique for producing a pure Bacteroides

fragilis infection in mice is described. The infection produces large

subcutaneous abscesses at the site of bacterial injection in approximately

90% of the mice. The abscess can be seen as an obvious swelling within 5-7 days post-injection. The infection was initiated by injection of pure cultures grown in a semisolid medium. Similar infections were also produced

with pure cultures of B. distasonis, B. ovatus, B. thetaiotaomicron, and B. vulgatus.

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