Type of Document Dissertation Author Walker, Clay B. URN etd-08012012-040709 Title Experimental anaerobic bacterial infections in mice Degree PhD Department Microbiology Advisory Committee
Advisor Name Title Wilkins, Tracy D. Committee Chair Cummins, C. S. Committee Member Gregory, Eugene M. Committee Member Krieg, Noel R. Committee Member Moore, W. E. C. Committee Member Keywords
Date of Defense 1977-06-15 Availability restricted AbstractThe development of a technique for producing a pure Bacteroides
fragilis infection in mice is described. The infection produces large
subcutaneous abscesses at the site of bacterial injection in approximately
90% of the mice. The abscess can be seen as an obvious swelling within 5-7 days post-injection. The infection was initiated by injection of pure cultures grown in a semisolid medium. Similar infections were also produced
with pure cultures of B. distasonis, B. ovatus, B. thetaiotaomicron, and B. vulgatus.
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