Type of Document	Master's Thesis
Author	Herfel, Tina Marie
URN	etd-08032007-191149
Title	A FORTY-NINE DAY EVALUATION OF BIO-MOS® REPLACEMENT OF ROXARSONE IN A COMMERICALLY BASED BROILER FEEDING PROGRAM
Degree	Master of Science
Department	Animal and Poultry Sciences
Advisory Committee	Advisor Name Title Novak, Curtis L. Committee Chair McElroy, Audrey P. Committee Member Pierson, Frank William Committee Member
Keywords	broiler coccidia roxarsone -Mos performance
Date of Defense	2007-07-23
Availability	restricted
Abstract A study was conducted to investigate the effects of roxarsone and Bio-Mos® on broiler production, gut morphology and bone strength. Three thousand and ten broilers were randomly assigned to 1 of 5 dietary corn-soybean meal based treatments: 1) negative control (NEG), basal diet; 2) positive control (POS; NEG + 27 ppm Bacitracin MD); 3) roxarsone (ROX; POS + 50 ppm of roxarsone); 4) Bio-Mos® (BIO; POS + 0.15 and 0.5% Bio-Mos® added during the starter and grower periods, respectively); 5) Bio-Mos®+All-Lac XCL (BIO+LAC; POS + 0.2, 0.1, and 0.05% Bio-Mos® during the starter, grower and finishing periods, respectively and 0.25g All-Lac XCL/bird sprayed at hatchery). On day 14, 7 of the 14 replicate pens/treatment were challenged with Eimeria maxima (3 x 104 oocysts/bird). Tibias were collected on day 28 and 49 to determine bone-breaking strength. Non-challenged birds had higher body weight gains (BWG) and lower feed conversion (FCR) from day 0 to 49 than challenged birds (P < 0.05). Jejunal crypt depth was increased in challenged broilers compared to non-challenged broilers at 28 days-of-age (P < 0.05). From day 0 to 35, ROX birds had lower BWG and FI than BIO and BIO+LAC birds (P < 0.05), while FCR was similar. Supplementing roxarsone resulted in reduced feed intake and BWG, but no significant differences were noted in FCR compared to feeding Bio-Mos®. ROX fed broilers had decreased ileal crypt depth compared to all other dietary treatments (P < 0.05). Muscle As concentration was lower than FDA allowable limits in broilers fed ROX without a withdrawal period at 28 days-of-age. Including roxarsone or Bio-Mos® did not generally improve production compared to broilers fed the negative diet.
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