Title page for ETD etd-11172012-040154
|Type of Document
||Hopkins, Katherine Lee
||In vitro characterization of aromatase, estrone sulfotransferase and estrone sulfatase activities in the porcine placenta and endometrium at 30, 60 and 90 days of gestation
||Master of Science
|Knight, James W.
|Beal, W. E.
|Frahm, Richard R.
|Notter, David R.
|Date of Defense
The purpose of this investigation was to characterize the activities of three
enzymes, aromatase, estrone (E1) sulfotransferase and E] sulfatase, in the porcine
placenta and endometrium on d 30, 60 and 90 of gestation. These enzymes play key
roles in determining in utero concentrations of estrogens. Days 30, 60 and 90 were
chosen because previous investigations had determined that these were times of
substantial changes in in vitro estrogen production by the porcine placenta and
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