Type of Document	Dissertation
Author	Dunnington, Elizabeth Ann
URN	etd-11292012-040248
Title	Selection for serum cholesterol, voluntary physical activity, 56- day body weight and feed intake in albino mice.
Degree	PhD
Department	Genetics
Advisory Committee	Advisor Name Title White, John M. Committee Chair Hinkelmann, Klaus H. Committee Member Siegel, Paul B. Committee Member Thye, Forrest W. Committee Member Vinson, William E. Committee Member
Keywords	Mice
Date of Defense	1978-01-15
Availability	restricted
Abstract A short-term selection experiment was conducted with ICR albino mice produced by the reciprocal crossing of two lines of unselected animals which had been random—bred for 28 generations. Lines were developed by selecting for maximum and minimum serum cholesterol (SC) (lines CH and CL), voluntary physical activity (lines AH and AL), 56-day body weight (lines WH and WL) and feed intake (lines IH and IL). An unselected, random-bred control line was maintained with each pair of divergent selected lines (CC, AC, NC and IC, respectively). In the lines selected for SC, physical activity and 56-day body weight, selection was based on individual performance. Twenty-five paired matings plus five extra paired matings were used to perpetuate the lines each generation for five generations. The feed intake lines were perpetuated by within-sex, full-sib family selection with 30 paired matings per generation for five generations.
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