

Type of Document Master's Thesis Author Bi, Feng Jr. Author's Email Address fbi@vt.edu URN etd-71498-12035 Title The Asymmetric Synthesis Of The C1'-C10' Portion Of Pamamycin-621A Degree Master of Science Department Chemistry Advisory Committee
Advisor Name Title Ducker, William A. Tanko, James M. Calter, Michael A. Committee Chair Keywords
- Pamamycin
- Lower Portion
- Synthesis
- Ketene
Date of Defense 1998-08-04 Availability unrestricted Abstract The Asymmetric Synthesis of the C1'-C10' Portion of Pamamycin-621AFeng Bi
(ABSTRACT)
This thesis describes the synthesis of the C1'-C10' portion 72 of the pamamycin-621A using a cuprate conjugate addition to join enone fragment 52 and organostannane fragment 64a. Fragments 52 and 64a were both synthesized from (S)-methylketene dimer 51.
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