ROANOKE TIMES

                         Roanoke Times
                 Copyright (c) 1995, Landmark Communications, Inc.

DATE: SATURDAY, March 16, 1991                   TAG: 9103160249
SECTION: NATIONAL/INTERNATIONAL                    PAGE: A-12   EDITION: METRO 
SOURCE: 
DATELINE:                                 LENGTH: Short


SCIENTISTS BLOCK CANCER GENE GROWTH

For the first time, researchers have successfully blocked the activity of a cancer gene to halt the growth of cancer cells in a test tube.

Because the new approach, reported Friday by researchers from the University of Texas, would affect only cancer cells, it would virtually eliminate all of the side effects now associated with radiation treatments and chemotherapy.

The Texas researchers caution, however, that the therapy will not be available to humans for many years.

Industrial and academic researchers throughout the United States have been intensively experimenting with the new approach, which involves the use of synthetic molecules called "antisense RNA." But their results have been disappointing so far, experts said, because the treatment seemed to work only sporadically.

Researchers at the M.D. Anderson Cancer Center in Houston, however, report in Friday's issue of the journal Cancer Research that their variation of the technique seems to work almost every time. They hope to start testing it shortly on tumors in mice. - Los Angeles Times



 by CNB