ROANOKE TIMES

                         Roanoke Times
                 Copyright (c) 1995, Landmark Communications, Inc.

DATE: SATURDAY, December 25, 1993                   TAG: 9312250093
SECTION: NATIONAL/INTERNATIONAL                    PAGE: A-1   EDITION: HOLIDAY 
SOURCE: Associated Press
DATELINE: WASHINGTON                                LENGTH: Medium


SMALLPOX VIRUS'S EXECUTION DATE POSTPONED

Smallpox will live to see another year.

Scientists in Atlanta and Moscow were scheduled to simultaneously destroy the world's last remaining smallpox virus on New Year's Eve. But the plan caused such a furor that history's deadliest disease has won a reprieve.

"We don't know just what the next step will be," said Chuck Fallis, spokesman for the Centers for Disease Control and Prevention. "They'll be meeting at some point after the first of the year to discuss it further."

Smallpox in 1977 became the only disease ever eradicated. But scientists preserved some of the live virus to study, frozen in 600 test tubes in heavily guarded laboratories at the CDC in Atlanta and at Russia's Institute for Viral Preparations.

In 1990, the World Health Organization asked the agencies to genetically map one strain of the virus and then, by flipping a switch to heat up the vials, destroy it all on Dec. 31.

The agencies agreed and have mapped two strains and are working on a third. But because those maps didn't yield enough information and because of a scientific outcry, WHO and the CDC agreed to postpone smallpox's execution date.

Dozens of researchers opposed deliberately destroying an entire species, particularly one that might teach them how to fight other diseases.

"Destroying all these vials now will compromise any possibilities of finding out more information," says Dr. Bernard Moss of the National Institutes of Health.

Smallpox still is a mystery - scientists don't even know how it kills. It claimed hundreds of millions of victims since its first recorded attack in ancient Egypt. One in four victims died, suffering convulsions, internal bleeding and painful lesions.

A vaccine was discovered in the 1790s, and smallpox took 200 years of immunizations to eradicate.

Next month, a WHO committee will meet to review just how much researchers have learned from genetically mapping smallpox and whether they expect more mapping will reveal any more.

That committee will report to the World Health Assembly, a group of representatives from all United Nations members who will again decide the virus' fate.

WHO says keeping the lethal virus around poses the risk of an accidental release or use by terrorists. The CDC dislikes using valuable space and money to guard smallpox in its top-security laboratory.

Other scientists argue that it's worth the risk to see if smallpox holds clues to eradicating other diseases, or if it might help them identify the way mysterious emerging diseases work.



 by CNB